Our teams: METHODS
I am a researcher in the METHODS team in CRESS UMR 1153 at Université Paris Cité. I am a registered pharmacist with training in public health, including a Master’s and a PhD in public health with specialization in epidemiology.
My work focuses on meta-research (i.e., research on research) to improve how evidence is generated, synthesized, and translated into decision-making. I have experience in evidence synthesis and guideline development, and have provided methodological support to inform decisions for local and international organizations, including the World Health Organization.
Currently, I focus on exploring the role of non-randomized studies, particularly target trial emulations, in supporting decision-making.
Research interests
- Target trial emulations
- Development and methodology of clinical practice guidelines
- Research methodology
Key publications
- Yaacoub S, Ioannidis JPA, Hróbjartsson A, Porcher R, Ravaud P, Boutron I. Factors influencing the trustworthiness of non-randomized studies of interventions: a survey of international experts. BMC Med. 2026
View publication - Yaacoub S, Porcher R, Pellat A, et al. Characteristics of non-randomised studies of drug treatments: cross sectional study. BMJ Med. 2024;3(1):e000932
View publication - Fraenkel, L., Bathon, J. M., England, B. R., St Clair, E. W., Arayssi, T., Carandang, K., Deane, K. D., Genovese, M., Huston, K. K., Kerr, G., Kremer, J., Nakamura, M. C., Russell, L. A., Singh, J. A., Smith, B. J., Sparks, J. A., Venkatachalam, S., Weinblatt, M. E., Al-Gibbawi, M., Baker, J. F., … Yaacoub, S., Akl, E. A. (2021). 2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis. Arthritis care & research, 73(7), 924–939.
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