Our teams: METHODS

A Professor of Biostatistics at Université Paris Cité, I am a member of the METHODS team at CRESS-UMR1153, hold a chair at the PR[AI]RIE Artificial Intelligence Institute, am the co-director of the Centre Virchow-Villermé. I also serve as the director of the College of Doctoral Studies at Université Paris Cité, and as a member of the Comité d’Evaluation Ethique/Institutional Review Board of Inserm.

With extensive expertise in biostatistics, I am actively involved in both statistical and applied clinical research, including clinical trials, observational studies, and prognostic studies. My research interests are centered on statistical and machine learning methods for personalized medicine and methods for causal inference on treatment effects, particularly through the use of clinical trials or observational studies. I am also a participant in several international projects, including NECESSITY (NEw Clinical Endpoints in primary Sjögren’s Syndrome: an Interventional Trial based on Stratifying Patients), funded by H2020-JTI-IMI2, and MORE-Europa (More Effectively Using Registries to Support Patient-centered Regulatory and HTA Decision-making), recently funded by Horizon Europe. I was previously the leader of the Work Package on Clinical Trials Designs for Personalized Medicine in the H2020-funded PERMIT (PERsonalised MedicIne Trials) project.

Research interests

  • Causal inference
  • Methods for personalized medicine

Key publications

  • Seror R, Baron G, Camus M, Cornec D, Perrodeau E, Bowman SJ, Bombardieri M, Bootsma H, Gottenberg JE, Fisher B, Hueber W, van Roon JA, Devauchelle-Pensec V, Gergely P, Mariette X, Porcher R; NECESSITY WP5 – STAR development working group; NECESSITY WP5- STAR development working group. Development and preliminary validation of the Sjögren’s Tool for Assessing Response (STAR): a consensual composite score for assessing treatment effect in primary Sjögren’s syndrome. Ann Rheum Dis. 2022
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  • Porcher R, Desguerre I, Amthor H, Chabrol B, Audic F, Rivier F, Isapof A, Tiffreau V, Campana-Salort E, Leturcq F, Tuffery-Giraud S, Ben Yaou R, Annane D, Amédro P, Barnerias C, Bécane HM, Béhin A, Bonnet D, Bassez G, Cossée M, de La Villéon G, Delcourte C, Fayssoil A, Fontaine B, Godart F, Guillaumont S, Jaillette E, Laforêt P, Leonard-Louis S, Lofaso F, Mayer M, Morales RJ, Meune C, Orlikowski D, Ovaert C, Prigent H, Saadi M, Sochala M, Tard C, Vaksmann G, Walther-Louvier U, Eymard B, Stojkovic T, Ravaud P, Duboc D, Wahbi K. Association between prophylactic angiotensin-converting enzyme inhibitors and overall survival in Duchenne muscular dystrophy-analysis of registry data. Eur Heart J. 2021
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  • Porcher R, Tran VT, Blacher J, Ravaud P. Potential of Stratified Medicine for High Blood Pressure Management: A Modeling Study Using NHANES Survey Data. Hypertension. 2019
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