I am a measurement scientist in mental health. My research focuses on strengthening the relevance, validity and consistency of measurement in clinical research and measurement-based care.
A central interest in my work is how to achieve greater harmonisation across studies and settings while ensuring that measurement remains person-centred and appropriate to context. This includes ensuring that patient priorities and lived experience inform what is measured, identifying common outcome domains and core measures that improve comparability, and considering where local adaptation or different measurement approaches are needed. I also work on evidence-based selection of measurement instruments through the systematic appraisal and synthesis of evidence on the psychometric properties of measurement instruments.
I have contributed to the development of international core outcome sets for anxiety and depression in children and young people, as well as guidance for systematic reviews of outcome measurement instruments. I am co-principal investigator of COLIVE-MH, a Wellcome-funded project developing an open-access evidence-synthesis platform to support the selection of patient-reported outcome measures in mental health. A related strand of my research examines the measurement and reporting of psychosocial and contextual patient characteristics in clinical trials, given their importance for investigating equity, external validity and treatment-effect heterogeneity.
I use evidence synthesis, mixed methods, consensus methods and participatory research involving people with lived experience. I hold an MSc in Political Sociology from the London School of Economics and Political Science and a PhD in Psychology from University College London.
Research interests
- Measurement science and harmonisation in mental health
- Measurement of outcomes and patient characteristics
- Mixeds methods and participatory research
- Child and youth mental health
Key publications
- Salman, M., Tran, V.-T., Boutron, I., Ravaud, P., Connell, S., & Krause, K. R. (2026). A scoping review of ICHOM Sets identifies a small number of commonly recommended baseline characteristics. Journal of Clinical Epidemiology, 112292. https://doi.org/https://doi.org/10.1016/j.jclinepi.2026.112292
View publication - Krause, K. R., Ravaud, P., & Tran, V.-T. (2025). Integrating personomics into precision medicine. Journal of Clinical Epidemiology, 184, 111859.
View publication - Krause, K.R., Chung, S., Adewuya, A. O., … Wolpert, M. (2021). International consensus on a standard set of outcome measures for child and youth anxiety, depression, obsessive-compulsive disorder, and post-traumatic stress disorder. The Lancet Psychiatry, Vol. 8(1), 76-86.
View publication - Krause, K. R., Chung, S., Sousa Fialho, Maria da Luz Szatmari, P., & Wolpert, M. (2021). The Challenge of Ensuring Affordability, Sustainability, Consistency, and Adaptability in the Common Metrics Agenda. The Lancet Psychiatry, Vol. 8(12), 1094-1102.
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