Our teams: METHODS

Anesthesia and Intensive Care research provides a large body of precious but potentially biased observational data.

Integrating these data with evidence from randomized controlled trials in a meta-analysis represents a methodological challenge, because of inherent differences between the two types of design.

We focus on the methods used by the authors of these meta-analyses to highlight their limitations and suggest improvements according to the recommendations.

Research interests

  • Observational studies and randomized controlled trials
  • Systematic review and meta-analysis
  • Intensive Care/ Anaesthesia and comparative effectiveness research

Key publications

  • Empirical evaluation of the methods used in systematic reviews including observational studies and randomized trials. J Clin Epidemiol. 2023
  • Synthesis methods used to combine observational studies and randomized trials in published meta-analyses. Systematic Reviews. 2023



Contribution of observational studies to network Meta-Analysis: the example of anaesthesiology

Cherifa Cheurfa

Promotion : 2018 - 2023

Supervisor.s : Isabelle Boutron, Anna Chaimani

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