Methods of therapeutic evaluation of chronic diseases

The objectives of the METHODS team are to rethink the therapeutic evaluation of chronic diseases, propose new concepts and develop new methodological approaches.

  • Building Evidence: new concepts, new methods

  • Rethinking Evidence Synthesis

  • Developing Research on Research

Visit the METHODS website


  • Pr. Isabelle Boutron
    Director of the team

  • Contact
    Audrey Conjaud, administrative assistant –

Major projects


Suggest ideas for research on chronic diseases.


INSPIRE is a major research project aimed at simplifying the collection, analysis and selection of research ideas from a large number of patients.

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Best practice journal research network


The development of an international “best practice journal research network” will promote evidence-based practice and address the need to increase the amount and quality of research by journals.

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MIROR project

Joint doctoral training programme

Miror Project

An joint doctoral training programme funded by Marie Skłodowska-Curie Actions, dedicated to Methods in Research on Research in the field of clinical research.

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Live NMA

Live cumulative network meta-analysis

live nma

We need a comprehensive, up-to-date synthesis of evidence for all treatments available for a given disease. We call this approach “live cumulative network meta-analysis”.

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Other links
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The focus of the French EQUATOR centre is on increasing/improving/enhancing the value of biomedical research

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E-cohort to advance research on chronic diseases.

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Philippe Ravaud and Isabelle Boutron are director and co-director of Cochrane France. The primary role of Cochrane France is to support Cochrane contributors in their area, and to act as a point of contact between Cochrane and their regional health communities.

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