Our teams: EPOPé

I belong to the EPOPé team's Axis 3: "Causes and consequences of prematurity". My research focuses on

  • assessment of the outcome of extremely premature infants in terms of neonatal mortality and morbidity, neurodevelopmental disorders, handicaps and weight and statural growth;
  • the study of late-onset neonatal sepsis (LOS), frequent complications of children born very prematurely, and their impact on the health of children in the longer term; and
  • the evaluation of medical practices, their evolution and their effects on the prognosis of extremely premature children.

Key publications

  • Diguisto C, Goffinet F, Lorthe E, Kayem G, Roze JC, Boileau P, Khoshnood B, Benhammou V, Langer B, Sentilhes L, Subtil D, Azria E, Kaminski M, Ancel PY, Foix–L’Hélias L. Providing active antenatal care depends on the place of birth for extremely preterm births: the EPIPAGE 2 cohort study. Arch Dis Child Fetal Neonatal Ed. 2017 Nov;102(6):F476-F482. doi: 10.1136/archdischild-2016-312322. Epub 2017 Jun 30.
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  • Letouzey M, Foix-L'Hélias L, Torchin H, Mitha A, Morgan AS, Zeitlin J, Kayem G, Maisonneuve E, Delorme P, Khoshnood B, Kaminski M, Ancel PY, Boileau P, Lorthe E; EPIPAGE-2 Working Group on Infections. Cause of preterm birth and late-onset sepsis in very preterm infants: the EPIPAGE-2 cohort study. Pediatr Res. 2021 Sep;90(3):584-592. doi: 10.1038/s41390-021-01411-y. Epub 2021 Feb 24.

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  • Letouzey M, Lorthe E, Marchand-Martin L, Kayem G, Charlier C, Butin M, Mitha A, Kaminski M, Benhammou V, Ancel PY, Boileau P, Foix-L'Hélias L; EPIPAGE-2 Infectious Diseases Working Group. Early Antibiotic Exposure and Adverse Outcomes in Very Preterm Infants at Low Risk of Early-Onset Sepsis: The EPIPAGE-2 Cohort Study. J Pediatr. 2022 Apr;243:91-98.e4. doi: 10.1016/j.jpeds.2021.11.075. Epub 2021 Dec 21. PMID: 34942178.
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