PhD student: Olivier Paccoud
Title: Optimising the management of invasive fungal infections in France using surveillance data through target trial emulation
Supervisors
- Pr Raphael Porcher, Centre de Recherche en Epidémiologie et Statistiques (CRESS)
- Pr Fanny Lanternier, Centre de Référence National des Mycoses invasives et des Antifongiques (CNRMA), Institut Pasteur, Paris
Doctoral school: ED393
Promotion: 2024/2025
Funding: Fixed-term contract, Plan d’investissement d’avenir, Projet PRAIRIE (PaRis Artificial Intelligence Research InstitutE)
Thesis abstract
The objectives of this thesis work are: 1) to identify the various limitations and biases of observational studies aimed at evaluating the effectiveness of therapeutic interventions in the field of medical mycology, 2) to formalize which methods or approaches can be implemented to address these issues, particularly within the framework of target trial emulation, and 3) to apply the identified approaches to answer a series of unresolved therapeutic questions in the field of invasive fungal infections in order to optimise their management in France.
