PhD student: Manel Ghozal
Title: Early life exposure to food chemicals and allergic and respiratory diseases in childhood
Supervisor: Blandine de Lauzon-Guillain
Doctoral school: ED 393 Epidemiology and Biomedical Information Sciences, Université Paris Cité
Promotion: 2021
Funding: INRAe
Thesis abstract:
Some studies have reported a positive association between early life exposure to food chemicals and the occurrence of allergies or asthma in children. However, there is few studies on the subject and the level of evidence is still very low. This work aims to identify the links between perinatal dietary exposure to a large set of chemicals and allergic or respiratory diseases in childhood. We use data from two French birth cohorts EDEN and ELFE, in which food consumption data were previously crossed with the total diet surveys by ANSES. In addition to individual chemicals, we will examine exposure to mixtures of food chemicals to consider the effects of co-exposures. First, we will focus on maternal dietary exposure to chemicals during pregnancy. Second, we will examine the effect of exposure to chemicals through infant’s diet in the first year of life.
