I am research professor at Inserm, and most of my research has been devoted to the development of epidemiological research on childhood cancers. One of my main areas of research aims to improve our knowledge of childhood cancer risk factors. I carried out several large-scale studies that have contributed to document the role of environmental, genetic, perinatal and lifestyle risk factors. I was a founding member of the CLIC international consortium, in which these studies actively participate. A growing part of my research is devoted to the long-term epidemiological follow-up of childhood cancer survivors. The development of national infrastructures capable of providing standardized and quality-controlled information on a comprehensive basis has been crucial to this area of research. I first committed myself in creating the National registry of childhood cancer (RNCE) and then in creating the Childhood Cancer Observation Platform (CCOP), which complements the RNCE with several databases, in particular the national COHOPER cohort of all patients diagnosed since 2000. The field is now developed by an entire team and can rely on priceless data from tens of thousands of children
Research interests
- Risk factors of childhood cancers
- Health of childhood cancer survivors
- Late effects of treatments
Key publications
- Mancini M, Hémon D, de Crouy-Chanel P, Guldner L, Faure L, Clavel J, Goujon S. Association between residential proximity to viticultural areas and childhood acute leukemia risk in mainland France – GEOCAP case-control study, 2002-2013 Environ Health Perspect 2023. In press. doi: 10.1289/EHP12634
- Ajrouche R, Chandab G, Petit A, Strullu M, Nelken B, Plat G, Michel G, Domenech C, Clavel J, Bonaventure A. Allergies, genetic polymorphisms of Th2 interleukins, and childhood acute lymphoblastic leukemia: The ESTELLE study.Pediatr Blood Cancer, 2022;69(3):e29402 PMID:34662484.
View publication - Poulalhon C, Vignon L, Idbrik L, Bernier-Chastagner V, Fabre M, Schleiermacher G, Dijoud F, Perrin C, Varlet P, Faure L, Guissou S, Désandes E, Hémon D, Berger C, Lacour B, Clavel J. Data Resource Profile: The French Childhood Cancer Observation Platform (CCOP).Int J Epidemiol, 2020;49(5):1434-5k PMID:32642766.
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