Objectives
The objective of GEOCAP-BIRTH, based on the National Childhood Cancer Registry, is to study the influence of environmental exposures on the risk of childhood cancer. This work is based on the home address of the cases at the time of their birth and on their location near sources of exposure or in relation to a cartography of exposure.
Methods
GEOCAP-BIRTH is a national case-control study in the general population.
The cases are all children born and diagnosed with cancer from 2010, residing in metropolitan France at the time of their diagnosis.
The controls are randomly selected by INSEE from the civil status database (≈2000/year), in order to be representative of births in metropolitan France.
| Inclusions 2010-2015 | N |
| Leukaemias | 980 |
| Lymphomas | 62 |
| Central nervous system tumours | 623 |
| Sympathetic nervous system tumours | 522 |
| Retinoblastomas | 216 |
| Renal tumours | 249 |
| Liver tumours | 62 |
| Bone tumours | 17 |
| Soft-tissue sarcomas | 180 |
| Germ-cell tumours | 108 |
| Total cases | 3 020 |
| Controls | 12 000 |
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- Geocoding and exposures assessment
The methodology is the same as that of GEOCAP
Regulatory aspects
CNIL 998198 v8.
Funding
Funding National Agency for Food, Environmental and Occupational Health Safety (ANSES)
Principal investigators
Jacqueline Clavel et Stéphanie Goujon
Collaborators
Cécile Chevrier et Bénédicte Jacquemin, IRSET, IRSN
